Antimicrobial peptide coated contact lenses

Antimicrobial peptide coated contact lenses may reduce risk of contact lens-related infections

Antimicrobial peptide coated contact lenses may reduce risk of contact lens-related infections

Studies in animals and now humans support the biocompatibility and safety of lenses coated with the antimicrobial peptide melimine, according to the new research by Debarun Dutta, B.Optom, of The University of New South Wales, Sydney, and colleagues. They write, "[T]his study has shown that melimine coated contact lenses can be safely worn by humans without any major side effects." Synthetic Coating Designed to Mimic Natural Infection-Fighting Peptides The researchers performed a series of experiments to evaluate the safety of contact lenses coated with melimine, designed to reduce the risk of inflammation and infections. Melimine is not an antibiotic-rather, it is a "cationic peptide" with broad-spectrum antimicrobial activity. "Antimicrobial peptides are small peptides and part of the innate immune system of all multicellular organisms with the native ability to inhibit microbial growth," Dr Dutta and colleagues explain. Melimine is among the first antimicrobial peptides to be tested for clinical use.…
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